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Lung Cancer Outlook Signature Test

Massachusetts rates for HCPCS 81538

A specialized laboratory test used in advanced lung cancer that measures a set of markers in a patient sample and combines them into a single result placing the person in a better or poorer outlook group. The result is used to help judge which type of treatment is most likely to benefit them.

Rates data updated July 2026.

Facilitymedian $5,754 · 10th–90th $2,138$8,5110%10%10th90th$5,754Professionalmedian $2,884 · 10th–90th $1,479$6,9180%20%40%10th90th$2,884$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$5,011.87
Typical High
$8,511.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,148.15
Median
$1,584.89
Typical High
$8,709.64
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$2,137.96
Median
$3,311.31
Typical High
$8,912.51
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,288.25
Median
$2,884.03
Typical High
$9,549.93
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,570.88
Median
$5,754.40
Typical High
$8,128.31
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,584.89
Median
$2,238.72
Typical High
$5,623.41
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$3,090.30
Typical High
$7,413.10
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$2,137.96
Median
$4,168.69
Typical High
$4,897.79
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$4,786.30
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$2,137.96
Median
$3,311.31
Typical High
$8,912.51
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,288.25
Median
$2,884.03
Typical High
$9,549.93
United
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$2,570.40
Typical High
$3,311.31
United
Setting
Professional
Modifier
Global
Typical Low
$1,288.25
Median
$2,884.03
Typical High
$5,495.41