Non-Invasive Prenatal Screening For Chromosome Conditions
Maryland rates for HCPCS 81420
This is a blood test done during pregnancy that analyzes small fragments of the baby's genetic material circulating in the mother's bloodstream to screen for certain chromosome conditions, such as Down syndrome. It only requires a blood draw from the mother, without any risk to the pregnancy. It's a screening test, meaning a positive result is typically followed by more definitive diagnostic testing.
Rates data updated October 2026.
How much does Non-Invasive Prenatal Screening For Chromosome Conditions cost?
$575
Typical negotiated rate. In Maryland, October 2026.
Insurers have agreed to pay about $575 for this service. Most negotiated rates run $501 to $603.
These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.
How much rates vary
Facilitymedian $562 · 10th to 90th $398 to $977Professionalmedian $575 · 10th to 90th $339 to $759
Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.
Rates by insurance carrier
Insurance Carrier
Facility/Professional
Modifier
Typical LowTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
MedianTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
Typical HighTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
Aetna
Setting
Facility
Modifier
None
Typical Low
$562.34
Median
$562.34
Typical High
$912.01
Facility
None
$562.34
$562.34
$912.01
Aetna
Setting
Professional
Modifier
None
Typical Low
$562.34
Median
$575.44
Typical High
$645.65
Professional
None
$562.34
$575.44
$645.65
CareFirst
Setting
Professional
Modifier
None
Typical Low
$549.54
Median
$602.56
Typical High
$616.60
Professional
None
$549.54
$602.56
$616.60
Cigna
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$524.81
Typical High
$977.24
Facility
None
$398.11
$524.81
$977.24
Cigna
Setting
Professional
Modifier
None
Typical Low
$398.11
Median
$724.44
Typical High
$2,187.76
Professional
None
$398.11
$724.44
$2,187.76
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$758.58
Median
$912.01
Typical High
$1,148.15
Professional
None
$758.58
$912.01
$1,148.15
United
Setting
Professional
Modifier
None
Typical Low
$331.13
Median
$380.19
Typical High
$676.08
Professional
None
$331.13
$380.19
$676.08
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$602.56
Typical High
$602.56
Professional
None
$380.19
$602.56
$602.56
2 more rates with less common billing modifiers
A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.
Insurance Carrier
Facility/Professional
Modifier
Typical LowTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
MedianTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
Typical HighTypical Low is the 10th percentile of the published rates, Median the 50th, and Typical High the 90th. One in ten rates falls below Typical Low, and one in ten falls above Typical High.
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$281.84
Median
$281.84
Typical High
$309.03
Professional
52 · Reduced service
$281.84
$281.84
$309.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$112.20
Median
$114.82
Typical High
$125.89
Professional
53 · Discontinued
$112.20
$114.82
$125.89
Where Maryland sits
The same service costs 3.4 times more in Alaska than in Maine. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.