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Non-Invasive Prenatal Screening For Chromosome Conditions

South Carolina rates for HCPCS 81420

This is a blood test done during pregnancy that analyzes small fragments of the baby's genetic material circulating in the mother's bloodstream to screen for certain chromosome conditions, such as Down syndrome. It only requires a blood draw from the mother, without any risk to the pregnancy. It's a screening test, meaning a positive result is typically followed by more definitive diagnostic testing.

Rates data updated July 2026.

How much does Non-Invasive Prenatal Screening For Chromosome Conditions cost?

$603

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $603 for this service. The price depends on where it is billed: about $589 from a physician practice, and about $1,413 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$589$589 to $617
FacilityA hospital or hospital-owned outpatient department$1,413$646 to $2,455

How much rates vary

Facilitymedian $1,413 · 10th to 90th $589 to $3,236Professionalmedian $589 · 10th to 90th $457 to $794
$10.0$100.0$1.0Kfacility $1,413professional $589

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$1,862.09
Typical High
$3,235.94
Aetna
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$676.08
BCBS
Setting
Facility
Modifier
Global
Typical Low
$794.33
Median
$954.99
Typical High
$2,290.87
BCBS
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$691.83
Typical High
$1,047.13
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,445.44
Median
$2,511.89
Typical High
$4,365.16
Cigna
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$416.87
Typical High
$912.01
Medcost
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$691.83
Typical High
$1,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$416.87
Median
$758.58
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$457.09
Typical High
$1,202.26

Where South Carolina sits

The same service costs 1.8 times more in Louisiana than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Carolina $603 · 42nd of 51
LA $912RI $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.