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Non-Invasive Prenatal Screening For Chromosome Conditions

Maine rates for HCPCS 81420

This is a blood test done during pregnancy that analyzes small fragments of the baby's genetic material circulating in the mother's bloodstream to screen for certain chromosome conditions, such as Down syndrome. It only requires a blood draw from the mother, without any risk to the pregnancy. It's a screening test, meaning a positive result is typically followed by more definitive diagnostic testing.

Rates data updated October 2026.

How much does Non-Invasive Prenatal Screening For Chromosome Conditions cost?

$501

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $501 for this service. The price depends on where it is billed: about $457 from a physician practice, and about $933 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$457$372 to $617
FacilityA hospital or hospital-owned outpatient department$933$741 to $1,122

How much rates vary

Facilitymedian $933 · 10th to 90th $741 to $1,122Professionalmedian $457 · 10th to 90th $302 to $794
$100$200$500$1K$2K$5Kfacility $933professional $457

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$977.24
Aetna
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$616.60
Typical High
$616.60
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$933.25
Typical High
$1,122.02
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$380.19
Typical High
$501.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$1,202.26
Median
$1,202.26
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
None
Typical Low
$691.83
Median
$776.25
Typical High
$870.96
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$758.58
Typical High
$1,412.54
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$977.24
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
United
Setting
Professional
Modifier
None
Typical Low
$457.09
Median
$478.63
Typical High
$1,412.54
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$263.03
Median
$309.03
Typical High
$309.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$104.71
Median
$123.03
Typical High
$123.03

Where Maine sits

The same service costs 3.4 times more in Alaska than in Maine. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 51st of 51

$501

AK $1,698ME $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.