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Non-Invasive Prenatal Screening For Chromosome Conditions

Pennsylvania rates for HCPCS 81420

This is a blood test done during pregnancy that analyzes small fragments of the baby's genetic material circulating in the mother's bloodstream to screen for certain chromosome conditions, such as Down syndrome. It only requires a blood draw from the mother, without any risk to the pregnancy. It's a screening test, meaning a positive result is typically followed by more definitive diagnostic testing.

Rates data updated July 2026.

How much does Non-Invasive Prenatal Screening For Chromosome Conditions cost?

$741

Typical negotiated rate. In Pennsylvania, July 2026.

Insurers have agreed to pay about $741 for this service. The price depends on where it is billed: about $617 from a physician practice, and about $1,175 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 13 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$617$550 to $724
FacilityA hospital or hospital-owned outpatient department$1,175$912 to $1,905

How much rates vary

Facilitymedian $1,175 · 10th to 90th $646 to $3,020Professionalmedian $617 · 10th to 90th $501 to $912
$500$1K$2K$5Kfacility $1,175professional $617

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$1,148.15
Typical High
$2,818.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$616.60
Typical High
$794.33
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$467.74
Typical High
$467.74
AmeriHealth
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$1,380.38
Typical High
$3,019.95
AmeriHealth
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$489.78
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$2,884.03
Median
$3,981.07
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$588.84
Median
$588.84
Typical High
$588.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$1,148.15
Typical High
$2,238.72
Cigna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$851.14
Typical High
$1,698.24
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$537.03
Typical High
$1,096.48
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$758.58
Median
$758.58
Typical High
$758.58
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$602.56
Median
$851.14
Typical High
$1,348.96
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$489.78
Median
$1,288.25
Typical High
$2,511.89
Highmark BCBS
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$575.44
Typical High
$870.96
Independence Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,230.27
Typical High
$2,691.53
Independence Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$489.78
Typical High
$758.58
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,174.90
Typical High
$3,235.94
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$616.60
Typical High
$1,778.28
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$1,348.96
Median
$1,380.38
Typical High
$1,949.84
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$1,659.59
Median
$2,754.23
Typical High
$4,897.79
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$660.69
Median
$758.58
Typical High
$891.25
United
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$758.58
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$457.09
Typical High
$1,148.15

Where Pennsylvania sits

The same service costs 1.8 times more in Louisiana than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 20th of 51

$741

LA $912RI $501

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.