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Definitive Drug Testing, Single Substance

Nationwide rates for HCPCS 80358

A laboratory test that identifies and measures one specific drug or its breakdown product in a sample, using precise instrument-based analysis rather than a quick presumptive screen. It confirms exactly what is present instead of only flagging a class of drug. It is used to confirm screening results and to check that prescribed treatment is being taken as directed.

Rates data updated July 2026.

Facilitymedian $7 · 10th–90th $0$830%10%10th90th$7Professionalmedian $15 · 10th–90th $5$400%20%10th90th$15$0.0$0.5$10.0$200.0$5.0K$100.0K$2.0M

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.03
Typical High
$0.10
Aetna
Setting
Professional
Modifier
Global
Typical Low
$0.02
Median
$0.04
Typical High
$19.50
BCBS
Setting
Facility
Modifier
Global
Typical Low
$5.13
Median
$18.62
Typical High
$32.36
BCBS
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$5.62
Typical High
$26.92
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1.35
Median
$50.12
Typical High
$138.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$25.12
Typical High
$42.66
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$14.45
Typical High
$26.92
United
Setting
Professional
Modifier
Global
Typical Low
$9.33
Median
$12.88
Typical High
$28.84