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Definitive Drug Testing, Single Substance

California rates for HCPCS 80358

A laboratory test that identifies and measures one specific drug or its breakdown product in a sample, using precise instrument-based analysis rather than a quick presumptive screen. It confirms exactly what is present instead of only flagging a class of drug. It is used to confirm screening results and to check that prescribed treatment is being taken as directed.

Rates data updated July 2026.

Facilitymedian $0 · 10th–90th $0$1510%20%10th90th$0Professionalmedian $22 · 10th–90th $5$470%20%10th90th$22$0.0$0.5$10.0$200.0$5.0K$100.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.04
Typical High
$0.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$0.02
Median
$0.02
Typical High
$0.06
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$21.88
Typical High
$21.88
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$5.25
Median
$6.03
Typical High
$6.03
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$5.13
Median
$22.39
Typical High
$51.29
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$15.85
Median
$22.39
Typical High
$38.90
Cigna
Setting
Facility
Modifier
Global
Typical Low
$0.48
Median
$0.72
Typical High
$5,623.41
Cigna
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$20.42
Typical High
$45.71
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$15.85
Median
$63.10
Typical High
$398.11
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$21.38
Typical High
$28.84
Molina
Setting
Professional
Modifier
Global
Typical Low
$19.95
Median
$19.95
Typical High
$19.95
Providence
Setting
Facility
Modifier
Global
Typical Low
$0.72
Median
$31.62
Typical High
$57.54
Providence
Setting
Professional
Modifier
Global
Typical Low
$12.88
Median
$15.85
Typical High
$50.12
United
Setting
Facility
Modifier
Global
Typical Low
$10.00
Median
$13.18
Typical High
$16.60
United
Setting
Professional
Modifier
Global
Typical Low
$9.55
Median
$14.45
Typical High
$56.23