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Definitive Drug Testing, Single Substance

Pennsylvania rates for HCPCS 80358

A laboratory test that identifies and measures one specific drug or its breakdown product in a sample, using precise instrument-based analysis rather than a quick presumptive screen. It confirms exactly what is present instead of only flagging a class of drug. It is used to confirm screening results and to check that prescribed treatment is being taken as directed.

Rates data updated July 2026.

Facilitymedian $0 · 10th–90th $0$00%50%90th$0Professionalmedian $15 · 10th–90th $0$290%20%10th90th$15$0.0$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.02
Typical High
$0.04
Aetna
Setting
Professional
Modifier
Global
Typical Low
$0.02
Median
$0.03
Typical High
$0.04
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$4.37
Median
$4.37
Typical High
$4.37
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$79.43
Median
$109.65
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$17.38
Typical High
$17.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$16.60
Median
$26.92
Typical High
$36.31
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$5.01
Median
$5.01
Typical High
$5.01
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$7.94
Median
$8.91
Typical High
$741.31
Highmark BCBS
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$15.49
Typical High
$15.49
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.02
Typical High
$0.04
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$0.02
Median
$0.03
Typical High
$0.07
United
Setting
Facility
Modifier
Global
Typical Low
$9.55
Median
$12.30
Typical High
$16.60
United
Setting
Professional
Modifier
Global
Typical Low
$9.55
Median
$15.49
Typical High
$33.88