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Definitive Drug Testing, Single Substance

South Carolina rates for HCPCS 80358

A laboratory test that identifies and measures one specific drug or its breakdown product in a sample, using precise instrument-based analysis rather than a quick presumptive screen. It confirms exactly what is present instead of only flagging a class of drug. It is used to confirm screening results and to check that prescribed treatment is being taken as directed.

Rates data updated October 2026.

How much does Definitive Drug Testing, Single Substance cost?

$14.45

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $14.45 for this service. Most negotiated rates run $11.22 to $23.44.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $14 · 10th to 90th $14 to $21Professionalmedian $14 · 10th to 90th $10 to $30
$10$20$50facility $14professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.96
Median
$18.62
Typical High
$25.12
Medcost
Setting
Facility
Modifier
None
Typical Low
$14.45
Median
$14.45
Typical High
$20.89
Medcost
Setting
Professional
Modifier
None
Typical Low
$20.42
Median
$20.42
Typical High
$26.30
Molina
Setting
Professional
Modifier
None
Typical Low
$30.20
Median
$30.20
Typical High
$30.20
United
Setting
Professional
Modifier
None
Typical Low
$10.00
Median
$13.18
Typical High
$26.30

Where South Carolina sits

The same service costs 19.5 times more in Alaska than in Georgia. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 35th of 51

$14.45

AK $100GA $5.13

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.