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Definitive Drug Testing, Single Substance

Massachusetts rates for HCPCS 80358

A laboratory test that identifies and measures one specific drug or its breakdown product in a sample, using precise instrument-based analysis rather than a quick presumptive screen. It confirms exactly what is present instead of only flagging a class of drug. It is used to confirm screening results and to check that prescribed treatment is being taken as directed.

Rates data updated July 2026.

Facilitymedian $48 · 10th–90th $18$950%20%40%10th90th$48Professionalmedian $13 · 10th–90th $13$340%50%90th$13$0.0$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$0.02
Median
$0.02
Typical High
$0.04
Aetna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$17.38
Typical High
$35.48
BCBS
Setting
Facility
Modifier
Global
Typical Low
$38.02
Median
$47.86
Typical High
$69.18
BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.62
Median
$18.62
Typical High
$20.89
Cigna
Setting
Facility
Modifier
Global
Typical Low
$0.56
Median
$0.56
Typical High
$1.51
Cigna
Setting
Professional
Modifier
Global
Typical Low
$14.45
Median
$25.12
Typical High
$93.33
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$40.74
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$34.67
Median
$34.67
Typical High
$40.74
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$30.90
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$11.48
Median
$17.38
Typical High
$35.48
Tufts
Setting
Facility
Modifier
Global
Typical Low
$13.49
Median
$30.20
Typical High
$112.20
United
Setting
Facility
Modifier
Global
Typical Low
$10.72
Median
$18.62
Typical High
$26.92
United
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$15.49
Typical High
$39.81