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Colon Cancer Gene Activity Recurrence Test

Nationwide rates for HCPCS 81525

A laboratory test run on colon tumor tissue removed at surgery that measures how active a group of genes is in the cancer cells. The result is a score estimating the chance the cancer will return, which helps the patient and oncologist decide whether chemotherapy after surgery is worthwhile.

Rates data updated July 2026.

Facilitymedian $4,571 · 10th–90th $2,512$12,3030%10%20%10th90th$4,571Professionalmedian $2,570 · 10th–90th $1,259$5,8880%20%10th90th$2,570$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,511.89
Median
$4,897.79
Typical High
$12,022.64
Aetna
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$2,511.89
Typical High
$5,888.44
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,754.23
Median
$4,168.69
Typical High
$13,182.57
BCBS
Setting
Professional
Modifier
Global
Typical Low
$851.14
Median
$1,258.93
Typical High
$4,677.35
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$6,309.57
Typical High
$13,489.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$3,715.35
Typical High
$7,413.10
United
Setting
Facility
Modifier
Global
Typical Low
$1,479.11
Median
$3,090.30
Typical High
$3,715.35
United
Setting
Professional
Modifier
Global
Typical Low
$1,318.26
Median
$1,862.09
Typical High
$4,677.35