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Colon Cancer Gene Activity Recurrence Test

Massachusetts rates for HCPCS 81525

A laboratory test run on colon tumor tissue removed at surgery that measures how active a group of genes is in the cancer cells. The result is a score estimating the chance the cancer will return, which helps the patient and oncologist decide whether chemotherapy after surgery is worthwhile.

Rates data updated July 2026.

Facilitymedian $6,166 · 10th–90th $2,291$9,1200%10%10th90th$6,166Professionalmedian $3,090 · 10th–90th $324$7,2440%50%10th90th$3,090$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$6,025.60
Typical High
$10,000.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$9,332.54
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$2,511.89
Typical High
$7,413.10
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$1,862.09
Typical High
$15,488.17
BCBS
Setting
Facility
Modifier
Global
Typical Low
$4,897.79
Median
$6,165.95
Typical High
$8,912.51
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,884.03
Median
$2,884.03
Typical High
$2,884.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$2,041.74
Median
$2,570.40
Typical High
$6,025.60
Cigna
Setting
Professional
Modifier
Global
Typical Low
$1,819.70
Median
$3,388.44
Typical High
$8,128.31
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$4,897.79
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$4,466.84
Typical High
$5,248.07
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$3,090.30
Median
$3,090.30
Typical High
$5,248.07
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$2,290.87
Median
$2,511.89
Typical High
$7,413.10
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$1,862.09
Typical High
$15,488.17
United
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$3,090.30
Typical High
$3,715.35
United
Setting
Professional
Modifier
Global
Typical Low
$1,862.09
Median
$3,090.30
Typical High
$6,165.95