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Colon Cancer Gene Activity Recurrence Test

Virginia rates for HCPCS 81525

A laboratory test run on colon tumor tissue removed at surgery that measures how active a group of genes is in the cancer cells. The result is a score estimating the chance the cancer will return, which helps the patient and oncologist decide whether chemotherapy after surgery is worthwhile.

Rates data updated October 2026.

How much does Colon Cancer Gene Activity Recurrence Test cost?

$2,344

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $2,344 for this service. The price depends on where it is billed: about $1,950 from a physician practice, and about $4,169 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,950$1,259 to $2,630
FacilityA hospital or hospital-owned outpatient department$4,169$3,090 to $7,244

How much rates vary

Facilitymedian $4,169 · 10th to 90th $3,090 to $13,183Professionalmedian $1,950 · 10th to 90th $1,259 to $4,074
$1K$2K$5K$10Kfacility $4,169professional $1,950

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,344.23
Median
$2,630.27
Typical High
$7,244.36
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,344.23
Median
$2,344.23
Typical High
$2,630.27
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$3,090.30
Median
$3,090.30
Typical High
$15,135.61
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$1,258.93
Median
$1,258.93
Typical High
$2,137.96
CareFirst
Setting
Professional
Modifier
None
Typical Low
$2,238.72
Median
$2,511.89
Typical High
$2,951.21
Cigna
Setting
Facility
Modifier
None
Typical Low
$3,162.28
Median
$6,025.60
Typical High
$9,332.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$1,548.82
Median
$2,238.72
Typical High
$5,248.07
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$2,951.21
Median
$3,388.44
Typical High
$4,365.16
Medcost
Setting
Facility
Modifier
None
Typical Low
$4,168.69
Median
$4,168.69
Typical High
$5,623.41
Medcost
Setting
Professional
Modifier
None
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$3,090.30
Sentara
Setting
Facility
Modifier
None
Typical Low
$2,818.38
Median
$4,466.84
Typical High
$11,481.54
Sentara
Setting
Professional
Modifier
None
Typical Low
$2,884.03
Median
$4,365.16
Typical High
$10,232.93
United
Setting
Facility
Modifier
None
Typical Low
$3,715.35
Median
$3,715.35
Typical High
$3,715.35
United
Setting
Professional
Modifier
None
Typical Low
$1,318.26
Median
$1,862.09
Typical High
$4,365.16
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,318.26
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$467.74
Median
$467.74
Typical High
$524.81

Where Virginia sits

The same service costs 6.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 38th of 51

$2,344

TX $7,943AL $1,318

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.