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Colon Cancer Gene Activity Recurrence Test

Nebraska rates for HCPCS 81525

A laboratory test run on colon tumor tissue removed at surgery that measures how active a group of genes is in the cancer cells. The result is a score estimating the chance the cancer will return, which helps the patient and oncologist decide whether chemotherapy after surgery is worthwhile.

Rates data updated October 2026.

How much does Colon Cancer Gene Activity Recurrence Test cost?

$1,862

Typical negotiated rate. In Nebraska, October 2026.

Insurers have agreed to pay about $1,862 for this service. The price depends on where it is billed: about $1,862 from a physician practice, and about $1,862 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$1,862$1,862 to $5,888
FacilityA hospital or hospital-owned outpatient department$1,862$1,380 to $3,236

How much rates vary

Facilitymedian $1,862 · 10th to 90th $1,202 to $7,413Professionalmedian $1,862 · 10th to 90th $1,778 to $15,488
$2K$5K$10Kfacility $1,862professional $1,862

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$2,041.74
Median
$7,413.10
Typical High
$15,488.17
Aetna
Setting
Professional
Modifier
None
Typical Low
$2,041.74
Median
$2,041.74
Typical High
$7,413.10
BCBS Nebraska
Setting
Facility
Modifier
None
Typical Low
$1,202.26
Median
$1,584.89
Typical High
$3,235.94
Cigna
Setting
Professional
Modifier
None
Typical Low
$5,754.40
Median
$5,888.44
Typical High
$7,413.10
Medica
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$3,890.45
Typical High
$14,791.08
Medica
Setting
Professional
Modifier
None
Typical Low
$1,862.09
Median
$1,862.09
Typical High
$15,488.17
Midlands
Setting
Professional
Modifier
None
Typical Low
$5,754.40
Median
$5,754.40
Typical High
$5,754.40
Midlands
Setting
Professional
Modifier
None
Typical Low
$5,754.40
Median
$5,754.40
Typical High
$5,754.40
United
Setting
Facility
Modifier
None
Typical Low
$1,122.02
Median
$1,318.26
Typical High
$1,862.09
United
Setting
Professional
Modifier
None
Typical Low
$1,778.28
Median
$1,862.09
Typical High
$9,332.54

Where Nebraska sits

The same service costs 6.0 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 45th of 51

$1,862

TX $7,943AL $1,318

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.