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Relative Exome Sequencing For Comparison

Nationwide rates for HCPCS 0215U

Sequences the protein-making portions of a family member's genes so they can be compared with an affected patient's results, which helps show whether a genetic change found in the patient is the likely cause of a rare inherited disorder. Mitochondrial DNA is read as well. Blood or saliva from the relative can be used.

Rates data updated June 2026.

Facilitymedian $4,074 · 10th–90th $2,138$11,7490%10%10th90th$4,074Professionalmedian $2,188 · 10th–90th $1,549$4,7860%20%10th90th$2,188$5.0$20.0$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$4,466.84
Typical High
$11,748.98
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$2,041.74
Typical High
$2,570.40
BCBS
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$4,897.79
Typical High
$12,302.69
BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,344.23
Median
$4,786.30
Typical High
$7,585.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$5,011.87
Typical High
$11,481.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$3,019.95
Median
$3,715.35
Typical High
$7,079.46
United
Setting
Facility
Modifier
Global
Typical Low
$1,202.26
Median
$2,570.40
Typical High
$3,090.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,548.82
Typical High
$3,090.30