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Relative Exome Sequencing For Comparison

California rates for HCPCS 0215U

Sequences the protein-making portions of a family member's genes so they can be compared with an affected patient's results, which helps show whether a genetic change found in the patient is the likely cause of a rare inherited disorder. Mitochondrial DNA is read as well. Blood or saliva from the relative can be used.

Rates data updated June 2026.

Facilitymedian $8,913 · 10th–90th $2,570$15,1360%5%10%10th90th$8,913Professionalmedian $2,291 · 10th–90th $1,549$7,2440%10%20%10th90th$2,291$100.0$500.0$2.0K$10.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,548.13
Median
$10,471.29
Typical High
$17,378.01
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,584.89
Median
$2,089.30
Typical High
$2,754.23
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$6,456.54
Median
$12,882.50
Typical High
$13,182.57
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$3,981.07
Median
$5,754.40
Typical High
$9,332.54
Blue Shield
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$5,888.44
Typical High
$7,585.78
Blue Shield
Setting
Professional
Modifier
Global
Typical Low
$1,513.56
Median
$1,995.26
Typical High
$4,466.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,737.80
Median
$4,168.69
Typical High
$8,709.64
Contra Costa Health
Setting
Professional
Modifier
Global
Typical Low
$2,570.40
Median
$2,818.38
Typical High
$3,467.37
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,818.38
Typical High
$4,466.84
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$12,302.69
Median
$12,302.69
Typical High
$12,302.69
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$12,882.50
Median
$19,498.45
Typical High
$19,498.45
Providence
Setting
Facility
Modifier
Global
Typical Low
$1,949.84
Median
$3,090.30
Typical High
$6,760.83
Providence
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$2,818.38
Typical High
$3,890.45
United
Setting
Facility
Modifier
Global
Typical Low
$1,071.52
Median
$2,570.40
Typical High
$3,090.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,071.52
Typical High
$5,128.61