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Relative Exome Sequencing For Comparison

Pennsylvania rates for HCPCS 0215U

Sequences the protein-making portions of a family member's genes so they can be compared with an affected patient's results, which helps show whether a genetic change found in the patient is the likely cause of a rare inherited disorder. Mitochondrial DNA is read as well. Blood or saliva from the relative can be used.

Rates data updated June 2026.

Facilitymedian $6,607 · 10th–90th $2,692$11,2200%10%10th90th$6,607Professionalmedian $2,042 · 10th–90th $1,445$2,5700%20%10th90th$2,042$1.0K$2.0K$5.0K$10.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,311.31
Median
$6,606.93
Typical High
$11,220.18
Aetna
Setting
Professional
Modifier
Global
Typical Low
$1,445.44
Median
$2,041.74
Typical High
$2,398.83
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$1,995.26
Median
$1,995.26
Typical High
$1,995.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$3,467.37
Typical High
$7,762.47
Cigna
Setting
Professional
Modifier
Global
Typical Low
$12,302.69
Median
$12,302.69
Typical High
$12,302.69
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$2,290.87
Median
$3,388.44
Typical High
$3,715.35
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$2,570.40
Typical High
$2,570.40
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$2,754.23
Median
$4,265.80
Typical High
$6,456.54
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$2,187.76
Median
$5,011.87
Typical High
$9,120.11
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$1,548.82
Median
$2,041.74
Typical High
$2,454.71
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$2,570.40
Median
$2,570.40
Typical High
$2,818.38
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$2,570.40
Median
$2,570.40
Typical High
$2,818.38
United
Setting
Facility
Modifier
Global
Typical Low
$1,548.82
Median
$2,570.40
Typical High
$3,090.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,548.82
Typical High
$3,467.37