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Relative Exome Sequencing For Comparison

Missouri rates for HCPCS 0215U

Sequences the protein-making portions of a family member's genes so they can be compared with an affected patient's results, which helps show whether a genetic change found in the patient is the likely cause of a rare inherited disorder. Mitochondrial DNA is read as well. Blood or saliva from the relative can be used.

Rates data updated July 2026.

How much does Relative Exome Sequencing For Comparison cost?

$4,074

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $4,074 for this service. The price depends on where it is billed: about $3,981 from a physician practice, and about $4,365 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$3,981$2,512 to $4,786
FacilityA hospital or hospital-owned outpatient department$4,365$3,090 to $4,898

How much rates vary

Facilitymedian $4,365 · 10th to 90th $2,570 to $6,026Professionalmedian $3,981 · 10th to 90th $1,549 to $4,786
$1K$2K$5K$10Kfacility $4,365professional $3,981

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$3,388.44
Median
$4,466.84
Typical High
$6,025.60
Aetna
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$4,365.16
Typical High
$8,912.51
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$2,511.89
Median
$4,466.84
Typical High
$4,786.30
Cigna
Setting
Facility
Modifier
Global
Typical Low
$3,630.78
Median
$5,370.32
Typical High
$13,182.57
Medica
Setting
Facility
Modifier
Global
Typical Low
$2,238.72
Median
$3,090.30
Typical High
$12,302.69
Medica
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,548.82
Typical High
$12,882.50
United
Setting
Facility
Modifier
Global
Typical Low
$1,071.52
Median
$2,570.40
Typical High
$3,090.30
United
Setting
Professional
Modifier
Global
Typical Low
$1,071.52
Median
$1,548.82
Typical High
$3,019.95

Where Missouri sits

The same service costs 3.7 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 6th of 51

$4,074

AK $5,754AL $1,549

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.