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In Situ Hybridization Tissue Test

Wyoming rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$776

Typical negotiated rate. In Wyoming, July 2026.

Insurers have agreed to pay about $776 for this service. Most negotiated rates run $525 to $1,230.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 3 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $776 · 10th to 90th $525 to $1,230
$100.0$200.0$500.0$1.0Kprofessional $776

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
BCBS
Setting
Professional
Modifier
Global
Typical Low
$524.81
Median
$776.25
Typical High
$1,230.27
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$79.43
Median
$120.23
Typical High
$190.55
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$436.52
Median
$660.69
Typical High
$1,047.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$630.96
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$97.72
Typical High
$269.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$74.13
Median
$537.03
Typical High
$1,479.11
United
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$245.47
Typical High
$831.76
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$40.74
Typical High
$134.90
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$199.53
Median
$208.93
Typical High
$691.83

Where Wyoming sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Wyoming $776 · 2nd of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.