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In Situ Hybridization Tissue Test

West Virginia rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$324

Typical negotiated rate. In West Virginia, October 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $324 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$200 to $457
FacilityA hospital or hospital-owned outpatient department$324$324 to $776

How much rates vary

Facilitymedian $324 · 10th to 90th $295 to $1,023Professionalmedian $324 · 10th to 90th $162 to $603
$100$200$500$1Kfacility $324professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$323.59
Typical High
$323.59
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$288.40
Median
$295.12
Typical High
$331.13
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$323.59
Typical High
$549.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$263.03
Median
$831.76
Typical High
$1,023.29
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$173.78
Median
$549.54
Typical High
$1,862.09
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$109.65
Typical High
$295.12
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$489.78
Typical High
$1,548.82
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$416.87
Typical High
$1,000.00
United
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$162.18
Median
$323.59
Typical High
$426.58
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$95.50
Typical High
$144.54
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$223.87
Typical High
$288.40
1 more rate with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Highmark BCBS
Setting
Professional
Modifier
59 · Distinct service
Typical Low
$467.74
Median
$467.74
Typical High
$467.74

Where West Virginia sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

West Virginia· 34th of 51

$324

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.