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In Situ Hybridization Tissue Test

Virginia rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$295

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $295 for this service. Most negotiated rates run $209 to $355.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $295 · 10th to 90th $166 to $603
$100$200$500$1Kprofessional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$331.13
Typical High
$660.69
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$56.23
Typical High
$107.15
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$239.88
Median
$275.42
Typical High
$549.54
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$165.96
Typical High
$316.23
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$26.92
Typical High
$52.48
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$141.25
Typical High
$269.15
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$380.19
Typical High
$446.68
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$63.10
Typical High
$83.18
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$354.81
Median
$363.08
Typical High
$426.58
Cigna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$223.87
Typical High
$676.08
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$37.15
Typical High
$120.23
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$181.97
Typical High
$575.44
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$489.78
Typical High
$562.34
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$60.26
Median
$72.44
Typical High
$85.11
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$316.23
Median
$416.87
Typical High
$478.63
Medcost
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$72.44
Typical High
$72.44
Sentara
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$275.42
Typical High
$776.25
Sentara
Setting
Professional
Modifier
26 · Professional part
Typical Low
$74.13
Median
$91.20
Typical High
$141.25
Sentara
Setting
Professional
Modifier
TC · Technical part
Typical Low
$165.96
Median
$234.42
Typical High
$794.33
United
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$338.84
Typical High
$660.69
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$67.61
Typical High
$134.90
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$275.42
Typical High
$549.54

Where Virginia sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 32nd of 51

$295

MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.