go back

In Situ Hybridization Tissue Test

Tennessee rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$437

Typical negotiated rate. In Tennessee, October 2026.

Insurers have agreed to pay about $437 for this service. Most negotiated rates run $245 to $1,349.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $692 · 10th to 90th $224 to $1,072Professionalmedian $372 · 10th to 90th $182 to $3,311
$100$200$500$1K$2Kfacility $692professional $372

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$288.40
Typical High
$288.40
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$288.40
Median
$309.03
Typical High
$380.19
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$50.12
Typical High
$61.66
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$239.88
Median
$257.04
Typical High
$316.23
Ambetter
Setting
Professional
Modifier
None (both parts)
Typical Low
$234.42
Median
$234.42
Typical High
$234.42
BCBS Tennessee
Setting
Professional
Modifier
None (both parts)
Typical Low
$194.98
Median
$371.54
Typical High
$724.44
BCBS Tennessee
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$87.10
Typical High
$120.23
BCBS Tennessee
Setting
Professional
Modifier
TC · Technical part
Typical Low
$151.36
Median
$309.03
Typical High
$602.56
Cigna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$691.83
Typical High
$1,071.52
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$177.83
Median
$229.09
Typical High
$549.54
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$61.66
Typical High
$120.23
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$229.09
Typical High
$467.74
Lucent Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$2,570.40
Median
$3,311.31
Typical High
$3,311.31
Lucent Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
Lucent Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$2,187.76
Median
$2,818.38
Typical High
$2,818.38
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$112.20
Median
$223.87
Typical High
$676.08
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$36.31
Median
$54.95
Typical High
$117.49
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$186.21
Typical High
$562.34
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$144.54
Median
$151.36
Typical High
$169.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$57.54
Median
$60.26
Typical High
$67.61

Where Tennessee sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 17th of 51

$437

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.