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In Situ Hybridization Tissue Test

Tennessee rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

Facilitymedian $479 · 10th–90th $30$4790%50%10th$479Professionalmedian $240 · 10th–90th $48$4470%10%10th90th$240$50.0$100.0$200.0$500.0$1.0K$2.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$309.03
Typical High
$389.05
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$53.70
Typical High
$87.10
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$239.88
Median
$257.04
Typical High
$323.59
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$234.42
Typical High
$234.42
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$29.51
Typical High
$87.10
BCBS
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$275.42
Typical High
$645.65
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$69.18
Typical High
$112.20
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$186.21
Typical High
$549.54
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$30.20
Median
$32.36
Typical High
$54.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$229.09
Typical High
$537.03
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$48.98
Typical High
$120.23
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$177.83
Typical High
$457.09
Lucent Health
Setting
Facility
Modifier
26 · Professional part
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$2,570.40
Median
$3,235.94
Typical High
$3,235.94
Lucent Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$512.86
Median
$512.86
Typical High
$512.86
Lucent Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$2,187.76
Median
$2,754.23
Typical High
$2,754.23
United
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$229.09
Typical High
$562.34
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$63.10
Typical High
$134.90
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$75.86
Median
$190.55
Typical High
$562.34