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In Situ Hybridization Tissue Test

Rhode Island rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$170

Typical negotiated rate. In Rhode Island, July 2026.

Insurers have agreed to pay about $170 for this service. Most negotiated rates run $166 to $389.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $170 · 10th to 90th $166 to $646
$100$200$500$1Kprofessional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$81.28
Median
$151.36
Typical High
$151.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$169.82
Typical High
$794.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$107.15
Typical High
$128.82
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$114.82
Median
$120.23
Typical High
$676.08
BCBS
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$389.05
Typical High
$389.05
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$61.66
Typical High
$87.10
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$331.13
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$323.59
Typical High
$676.08
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$91.20
Typical High
$107.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$181.97
Median
$229.09
Typical High
$575.44
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$426.58
Typical High
$645.65
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$74.13
Typical High
$102.33
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$363.08
Typical High
$537.03

Where Rhode Island sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 51st of 51

$170

MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.