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In Situ Hybridization Tissue Test

Rhode Island rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$288

Typical negotiated rate. In Rhode Island, October 2026.

Insurers have agreed to pay about $288 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $224 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$200 to $427
FacilityA hospital or hospital-owned outpatient department$224$200 to $309

How much rates vary

Facilitymedian $224 · 10th to 90th $195 to $1,000Professionalmedian $324 · 10th to 90th $166 to $575
$100$200$500$1Kfacility $224professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$165.96
Median
$165.96
Typical High
$199.53
BCBS Rhode Island
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$223.87
Typical High
$239.88
BCBS Rhode Island
Setting
Professional
Modifier
None (both parts)
Typical Low
$288.40
Median
$389.05
Typical High
$389.05
BCBS Rhode Island
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$61.66
Typical High
$97.72
BCBS Rhode Island
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$281.84
Typical High
$331.13
Cigna
Setting
Facility
Modifier
None
Typical Low
$602.56
Median
$1,000.00
Typical High
$1,047.13
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$213.80
Median
$213.80
Typical High
$562.34
United
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$380.19
Typical High
$380.19
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$114.82
Median
$426.58
Typical High
$724.44

Where Rhode Island sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 42nd of 51

$288

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.