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In Situ Hybridization Tissue Test

Rhode Island rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

Facilitymedian $151 · 10th–90th $81$1510%50%10th$151Professionalmedian $120 · 10th–90th $48$3890%20%10th90th$120$50.0$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Small sample; interpret with caution. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$81.28
Median
$151.36
Typical High
$151.36
Aetna
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$169.82
Typical High
$794.33
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$107.15
Typical High
$128.82
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$114.82
Median
$120.23
Typical High
$676.08
BCBS
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$389.05
Typical High
$389.05
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$61.66
Typical High
$87.10
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$331.13
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$323.59
Typical High
$676.08
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$91.20
Typical High
$107.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$181.97
Median
$229.09
Typical High
$575.44
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$426.58
Typical High
$645.65
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$32.36
Median
$74.13
Typical High
$102.33
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$72.44
Median
$363.08
Typical High
$537.03