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In Situ Hybridization Tissue Test

Oregon rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$468

Typical negotiated rate. In Oregon, July 2026.

Insurers have agreed to pay about $468 for this service. Most negotiated rates run $380 to $741.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $468 · 10th to 90th $269 to $1,148
$100.0$200.0$500.0$1.0Kprofessional $468

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$436.52
Typical High
$707.95
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$56.23
Median
$64.57
Typical High
$181.97
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$323.59
Median
$371.54
Typical High
$616.60
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$346.74
Typical High
$602.56
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$53.70
Typical High
$107.15
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$128.82
Median
$295.12
Typical High
$512.86
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$380.19
Median
$758.58
Typical High
$1,174.90
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$60.26
Median
$123.03
Typical High
$186.21
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$323.59
Median
$645.65
Typical High
$977.24
Moda Health
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$758.58
Typical High
$1,288.25
Moda Health
Setting
Professional
Modifier
26 · Professional part
Typical Low
$91.20
Median
$109.65
Typical High
$204.17
Moda Health
Setting
Professional
Modifier
TC · Technical part
Typical Low
$478.63
Median
$741.31
Typical High
$1,096.48
Pacific Source
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$645.65
Providence
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$724.44
Typical High
$1,174.90
Providence
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$63.10
Typical High
$181.97
Providence
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$295.12
Typical High
$933.25
Regence BlueShield
Setting
Professional
Modifier
Global
Typical Low
$575.44
Median
$851.14
Typical High
$1,258.93
Regence BlueShield
Setting
Professional
Modifier
26 · Professional part
Typical Low
$89.13
Median
$128.82
Typical High
$199.53
Regence BlueShield
Setting
Professional
Modifier
TC · Technical part
Typical Low
$478.63
Median
$724.44
Typical High
$1,071.52
United
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$363.08
Typical High
$1,258.93
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$64.57
Typical High
$194.98
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$199.53
Median
$257.04
Typical High
$1,047.13

Where Oregon sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Oregon $468 · 10th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.