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In Situ Hybridization Tissue Test

Oklahoma rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$275

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $275 for this service. Most negotiated rates run $275 to $468.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $275 · 10th to 90th $85 to $513
$100.0$200.0$500.0$1.0K$2.0Kprofessional $275

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$467.74
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$46.77
Typical High
$81.28
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$229.09
Typical High
$389.05
BCBS
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$239.88
Typical High
$512.86
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$199.53
Typical High
$660.69
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$33.11
Typical High
$102.33
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$60.26
Median
$151.36
Typical High
$549.54
Medica
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$407.38
Typical High
$2,570.40
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$67.61
Typical High
$398.11
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$234.42
Typical High
$2,187.76
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$245.47
Typical High
$724.44
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$144.54
Typical High
$316.23
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$346.74
Typical High
$1,659.59

Where Oklahoma sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Oklahoma $275 · 41st of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.