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In Situ Hybridization Tissue Test

Oklahoma rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$245

Typical negotiated rate. In Oklahoma, October 2026.

Insurers have agreed to pay about $245 for this service. The price depends on where it is billed: about $339 from a physician practice, and about $204 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$339$135 to $525
FacilityA hospital or hospital-owned outpatient department$204$135 to $282

How much rates vary

Facilitymedian $204 · 10th to 90th $112 to $490Professionalmedian $339 · 10th to 90th $78 to $2,570
$100$200$500$1K$2Kfacility $204professional $339

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$281.84
Typical High
$281.84
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$199.53
Median
$275.42
Typical High
$501.19
BCBS Oklahoma
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$144.54
Typical High
$204.17
BCBS Oklahoma
Setting
Professional
Modifier
None (both parts)
Typical Low
$63.10
Median
$245.47
Typical High
$524.81
Cigna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$891.25
Typical High
$891.25
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$114.82
Median
$169.82
Typical High
$316.23
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$29.51
Typical High
$100.00
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$141.25
Typical High
$213.80
Medica
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$288.40
Typical High
$1,778.28
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$245.47
Median
$2,570.40
Typical High
$2,570.40
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$398.11
Typical High
$398.11
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$194.98
Median
$2,187.76
Typical High
$2,187.76
United
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$275.42
Typical High
$446.68
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$134.90
Median
$407.38
Typical High
$630.96

Where Oklahoma sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 49th of 51

$245

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.