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In Situ Hybridization Tissue Test

Ohio rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$288

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $288 for this service. Most negotiated rates run $182 to $339.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 10 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $288 · 10th to 90th $162 to $447
$50.0$100.0$200.0$500.0$1.0K$2.0Kprofessional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$288.40
Typical High
$338.84
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$47.86
Typical High
$54.95
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$245.47
Typical High
$281.84
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$29.51
Typical High
$29.51
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$208.93
Typical High
$457.09
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$34.67
Typical High
$107.15
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$177.83
Typical High
$380.19
Aultcare
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$288.40
Typical High
$724.44
Aultcare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$45.71
Median
$47.86
Typical High
$120.23
Aultcare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$229.09
Median
$239.88
Typical High
$602.56
CareSource
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$288.40
Typical High
$467.74
Cigna
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$263.03
Typical High
$575.44
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$58.88
Typical High
$117.49
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$177.83
Typical High
$457.09
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$245.47
Typical High
$549.54
Medical Mutual of Ohio
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$64.57
Typical High
$141.25
Medical Mutual of Ohio
Setting
Professional
Modifier
TC · Technical part
Typical Low
$83.18
Median
$177.83
Typical High
$457.09
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$33.11
Typical High
$33.11
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$426.58
Typical High
$602.56
SummaCare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$63.10
Median
$72.44
Typical High
$100.00
SummaCare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$208.93
Median
$354.81
Typical High
$501.19
United
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$302.00
Typical High
$691.83
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$67.61
Typical High
$251.19
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$117.49
Median
$245.47
Typical High
$588.84

Where Ohio sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Ohio $288 · 38th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.