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In Situ Hybridization Tissue Test

New Mexico rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$295

Typical negotiated rate. In New Mexico, July 2026.

Insurers have agreed to pay about $295 for this service. Most negotiated rates run $251 to $347.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $295 · 10th to 90th $132 to $447
$50.0$100.0$200.0$500.0$1.0Kprofessional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$74.13
Median
$74.13
Typical High
$112.20
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$302.00
Typical High
$446.68
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$58.88
Median
$147.91
Typical High
$436.52
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$371.54
Typical High
$549.54
BCBS
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$165.96
Typical High
$478.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$281.84
Typical High
$478.63
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$61.66
Median
$77.62
Typical High
$102.33
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$147.91
Median
$194.98
Typical High
$389.05
Providence
Setting
Professional
Modifier
Global
Typical Low
$223.87
Median
$363.08
Typical High
$1,071.52
Providence
Setting
Professional
Modifier
26 · Professional part
Typical Low
$61.66
Median
$83.18
Typical High
$102.33
Providence
Setting
Professional
Modifier
TC · Technical part
Typical Low
$154.88
Median
$199.53
Typical High
$389.05
United
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$245.47
Typical High
$660.69
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$40.74
Typical High
$128.82
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$208.93
Typical High
$549.54

Where New Mexico sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

New Mexico $295 · 35th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.