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In Situ Hybridization Tissue Test

New Jersey rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$339

Typical negotiated rate. In New Jersey, October 2026.

Insurers have agreed to pay about $339 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $7,762 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$204 to $407
FacilityA hospital or hospital-owned outpatient department$7,762$537 to $16,982

How much rates vary

Facilitymedian $7,762 · 10th to 90th $155 to $22,387Professionalmedian $324 · 10th to 90th $129 to $646
$200$500$1K$2K$5K$10K$20Kfacility $7,762professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$154.88
Typical High
$154.88
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$37.15
Median
$44.67
Typical High
$44.67
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$93.33
Median
$109.65
Typical High
$181.97
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$128.82
Median
$181.97
Typical High
$724.44
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$39.81
Typical High
$104.71
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$109.65
Typical High
$616.60
AmeriHealth
Setting
Facility
Modifier
None
Typical Low
$11,220.18
Median
$16,595.87
Typical High
$25,703.96
AmeriHealth
Setting
Professional
Modifier
None (both parts)
Typical Low
$478.63
Median
$478.63
Typical High
$707.95
Cigna
Setting
Facility
Modifier
None
Typical Low
$489.78
Median
$741.31
Typical High
$1,288.25
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$128.82
Median
$229.09
Typical High
$630.96
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$34.67
Median
$66.07
Typical High
$123.03
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$91.20
Median
$162.18
Typical High
$489.78
Emblem Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$295.12
Median
$575.44
Typical High
$575.44
Horizon BCBS
Setting
Facility
Modifier
None
Typical Low
$398.11
Median
$10,964.78
Typical High
$23,988.33
Horizon BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$338.84
Median
$338.84
Typical High
$691.83
Horizon BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$51.29
Median
$51.29
Typical High
$123.03
Horizon BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$288.40
Median
$288.40
Typical High
$562.34
United
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$707.95
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$165.96
Median
$309.03
Typical High
$588.84
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$53.70
Typical High
$97.72
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$263.03
Typical High
$512.86
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$64.57
Median
$77.62
Typical High
$154.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$30.90
Typical High
$61.66

Where New Jersey sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New Jersey· 32nd of 51

$339

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.