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In Situ Hybridization Tissue Test

New Hampshire rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$537

Typical negotiated rate. In New Hampshire, October 2026.

Insurers have agreed to pay about $537 for this service. The price depends on where it is billed: about $537 from a physician practice, and about $603 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$537$389 to $933
FacilityA hospital or hospital-owned outpatient department$603$257 to $955

How much rates vary

Facilitymedian $603 · 10th to 90th $200 to $1,479Professionalmedian $537 · 10th to 90th $182 to $1,318
$200$500$1K$2Kfacility $603professional $537

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$954.99
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$181.97
Median
$181.97
Typical High
$371.54
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$257.04
Median
$288.40
Typical High
$630.96
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$154.88
Median
$645.65
Typical High
$1,318.26
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$97.72
Typical High
$199.53
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$549.54
Typical High
$1,096.48
Cigna
Setting
Facility
Modifier
None
Typical Low
$630.96
Median
$1,288.25
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$194.98
Median
$389.05
Typical High
$1,122.02
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$63.10
Typical High
$169.82
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$154.88
Median
$323.59
Typical High
$954.99
Harvard Pilgrim
Setting
Professional
Modifier
None (both parts)
Typical Low
$407.38
Median
$588.84
Typical High
$1,348.96
Harvard Pilgrim
Setting
Professional
Modifier
26 · Professional part
Typical Low
$66.07
Median
$93.33
Typical High
$213.80
Harvard Pilgrim
Setting
Professional
Modifier
TC · Technical part
Typical Low
$346.74
Median
$489.78
Typical High
$1,148.15
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$257.04
Median
$426.58
Typical High
$724.44

Where New Hampshire sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New Hampshire· 11th of 51

$537

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.