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In Situ Hybridization Tissue Test

North Dakota rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$676

Typical negotiated rate. In North Dakota, October 2026.

Insurers have agreed to pay about $676 for this service. Most negotiated rates run $288 to $891.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $288 · 10th to 90th $174 to $1,148Professionalmedian $813 · 10th to 90th $288 to $1,000
$100$200$500$1K$2Kfacility $288professional $813

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$288.40
Typical High
$977.24
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$190.55
Median
$288.40
Typical High
$524.81
BCBS North Dakota
Setting
Professional
Modifier
None (both parts)
Typical Low
$676.08
Median
$851.14
Typical High
$1,023.29
BCBS North Dakota
Setting
Professional
Modifier
26 · Professional part
Typical Low
$107.15
Median
$138.04
Typical High
$162.18
BCBS North Dakota
Setting
Professional
Modifier
TC · Technical part
Typical Low
$562.34
Median
$707.95
Typical High
$870.96
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$512.86
Median
$512.86
Typical High
$645.65
Medica
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$288.40
Typical High
$1,148.15
Medica
Setting
Professional
Modifier
None (both parts)
Typical Low
$812.83
Median
$912.01
Typical High
$2,570.40
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$416.87
Median
$851.14
Typical High
$933.25
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
BCBS North Dakota
Setting
Professional
Modifier
22 · Increased work
Typical Low
$812.83
Median
$1,023.29
Typical High
$1,230.27
BCBS North Dakota
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$134.90
Median
$169.82
Typical High
$204.17

Where North Dakota sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Dakota· 4th of 51

$676

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.