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In Situ Hybridization Tissue Test

Mississippi rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$372

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $372 for this service. Most negotiated rates run $282 to $617.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $372 · 10th to 90th $200 to $661
$50$100$200$500$1Kprofessional $372

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$588.84
Typical High
$660.69
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$104.71
Typical High
$117.49
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$234.42
Median
$478.63
Typical High
$549.54
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$31.62
Median
$31.62
Typical High
$39.81
BCBS
Setting
Professional
Modifier
Global
Typical Low
$371.54
Median
$371.54
Typical High
$371.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$239.88
Typical High
$602.56
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$79.43
Typical High
$125.89
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$141.25
Median
$218.78
Typical High
$489.78
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$32.36
Typical High
$33.11
United
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$407.38
Typical High
$660.69
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$74.13
Typical High
$141.25
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$109.65
Median
$302.00
Typical High
$549.54

Where Mississippi sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Mississippi· 14th of 51

$372

MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.