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In Situ Hybridization Tissue Test

Louisiana rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$257

Typical negotiated rate. In Louisiana, October 2026.

Insurers have agreed to pay about $257 for this service. The price depends on where it is billed: about $407 from a physician practice, and about $229 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$407$209 to $447
FacilityA hospital or hospital-owned outpatient department$229$195 to $339

How much rates vary

Facilitymedian $229 · 10th to 90th $195 to $427Professionalmedian $407 · 10th to 90th $170 to $562
$100$200$500$1Kfacility $229professional $407

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$407.38
Median
$407.38
Typical High
$446.68
Aetna
Setting
Facility
Modifier
TC · Technical part
Typical Low
$346.74
Median
$436.52
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$208.93
Median
$416.87
Typical High
$660.69
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$70.79
Typical High
$117.49
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$147.91
Median
$346.74
Typical High
$549.54
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS Louisiana
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$281.84
Typical High
$407.38
BCBS Louisiana
Setting
Professional
Modifier
None (both parts)
Typical Low
$269.15
Median
$446.68
Typical High
$467.74
BCBS Louisiana
Setting
Professional
Modifier
26 · Professional part
Typical Low
$74.13
Median
$74.13
Typical High
$87.10
BCBS Louisiana
Setting
Professional
Modifier
TC · Technical part
Typical Low
$186.21
Median
$363.08
Typical High
$389.05
Christus
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$194.98
Christus
Setting
Professional
Modifier
26 · Professional part
Typical Low
$60.26
Median
$60.26
Typical High
$60.26
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$851.14
Typical High
$1,548.82
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$117.49
Median
$177.83
Typical High
$588.84
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$31.62
Typical High
$102.33
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$70.79
Median
$147.91
Typical High
$489.78
United
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$257.04
Typical High
$478.63
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$131.83
Median
$281.84
Typical High
$575.44
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$67.61
Typical High
$117.49
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$208.93
Typical High
$489.78
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$173.78
Median
$218.78
Typical High
$776.25
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$69.18
Median
$87.10
Typical High
$309.03
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$125.89
Median
$208.93
Typical High
$239.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$50.12
Median
$83.18
Typical High
$95.50

Where Louisiana sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Louisiana· 48th of 51

$257

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.