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In Situ Hybridization Tissue Test

Louisiana rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$417

Typical negotiated rate. In Louisiana, July 2026.

Insurers have agreed to pay about $417 for this service. Most negotiated rates run $251 to $447.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $417 · 10th to 90th $191 to $661
$100$200$500professional $417

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$63.10
Median
$63.10
Typical High
$63.10
Aetna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$416.87
Typical High
$660.69
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$72.44
Typical High
$117.49
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$213.80
Median
$346.74
Typical High
$549.54
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$58.88
Median
$58.88
Typical High
$58.88
BCBS
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$446.68
Typical High
$501.19
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$74.13
Median
$74.13
Typical High
$89.13
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$162.18
Median
$363.08
Typical High
$416.87
Christus
Setting
Professional
Modifier
26 · Professional part
Typical Low
$58.88
Median
$60.26
Typical High
$60.26
Cigna
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$177.83
Typical High
$602.56
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$44.67
Typical High
$114.82
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$66.07
Median
$138.04
Typical High
$524.81
United
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$316.23
Typical High
$691.83
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$67.61
Typical High
$123.03
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$245.47
Typical High
$562.34

Where Louisiana sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Louisiana· 12th of 51

$417

MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.