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In Situ Hybridization Tissue Test

Kentucky rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$195

Typical negotiated rate. In Kentucky, July 2026.

Insurers have agreed to pay about $195 for this service. Most negotiated rates run $155 to $288.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $195 · 10th to 90th $141 to $372
$50.0$100.0$200.0$500.0$1.0Kprofessional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$288.40
Typical High
$354.81
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$46.77
Median
$47.86
Typical High
$64.57
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$131.83
Median
$239.88
Typical High
$295.12
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$154.88
Median
$154.88
Typical High
$194.98
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$26.92
Typical High
$63.10
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$128.82
Median
$128.82
Typical High
$141.25
CareSource
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$302.00
Typical High
$467.74
Cigna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$36.31
Median
$169.82
Typical High
$245.47
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$407.38
Typical High
$1,862.09
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$75.86
Typical High
$295.12
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$144.54
Median
$346.74
Typical High
$1,548.82
Molina
Setting
Professional
Modifier
Global
Typical Low
$32.36
Median
$32.36
Typical High
$33.11
United
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$363.08
Typical High
$616.60
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$51.29
Median
$67.61
Typical High
$128.82
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$134.90
Median
$295.12
Typical High
$512.86

Where Kentucky sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Kentucky $195 · 49th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.