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In Situ Hybridization Tissue Test

Hawaii rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$537

Typical negotiated rate. In Hawaii, October 2026.

Insurers have agreed to pay about $537 for this service. Most negotiated rates run $513 to $537.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $537 · 10th to 90th $309 to $603
$100$200$500professional $537

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$218.78
Typical High
$724.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$537.03
HMSA
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$512.86
Typical High
$537.03
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$562.34
Typical High
$831.76
United
Setting
Professional
Modifier
None
Typical Low
$537.03
Median
$537.03
Typical High
$691.83
University Health Alliance
Setting
Professional
Modifier
None
Typical Low
$309.03
Median
$309.03
Typical High
$309.03

Where Hawaii sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Hawaii· 10th of 51

$537

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.