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In Situ Hybridization Tissue Test

Georgia rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$363

Typical negotiated rate. In Georgia, October 2026.

Insurers have agreed to pay about $363 for this service. The price depends on where it is billed: about $363 from a physician practice, and about $347 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$363$166 to $661
FacilityA hospital or hospital-owned outpatient department$347$195 to $457

How much rates vary

Facilitymedian $347 · 10th to 90th $138 to $724Professionalmedian $363 · 10th to 90th $110 to $955
$100$200$500$1Kfacility $347professional $363

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$281.84
Typical High
$363.08
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$281.84
Median
$331.13
Typical High
$1,698.24
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$42.66
Median
$54.95
Typical High
$275.42
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$239.88
Median
$275.42
Typical High
$1,412.54
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.20
Median
$107.15
Typical High
$117.49
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$309.03
Typical High
$457.09
Anthem BCBS
Setting
Professional
Modifier
None (both parts)
Typical Low
$141.25
Median
$346.74
Typical High
$954.99
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$21.38
Median
$66.07
Typical High
$151.36
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$125.89
Median
$186.21
Typical High
$794.33
CareSource
Setting
Professional
Modifier
None (both parts)
Typical Low
$70.79
Median
$346.74
Typical High
$467.74
Cigna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$616.60
Typical High
$1,000.00
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$102.33
Median
$269.15
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$60.26
Typical High
$234.42
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$69.18
Median
$177.83
Typical High
$1,258.93
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$489.78
Typical High
$1,202.26
Oscar Health
Setting
Professional
Modifier
None (both parts)
Typical Low
$66.07
Median
$389.05
Typical High
$758.58
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$223.87
Median
$407.38
Typical High
$1,071.52
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$72.44
Typical High
$173.78
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$158.49
Median
$346.74
Typical High
$912.01
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$141.25
Median
$141.25
Typical High
$181.97
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$56.23
Median
$56.23
Typical High
$72.44

Where Georgia sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Georgia· 27th of 51

$363

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.