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In Situ Hybridization Tissue Test

Delaware rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$269

Typical negotiated rate. In Delaware, October 2026.

Insurers have agreed to pay about $269 for this service. The price depends on where it is billed: about $269 from a physician practice, and about $437 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$269$191 to $347
FacilityA hospital or hospital-owned outpatient department$437$347 to $832

How much rates vary

Facilitymedian $437 · 10th to 90th $224 to $912Professionalmedian $269 · 10th to 90th $117 to $427
$100$200$500$1K$2Kfacility $437professional $269

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$346.74
Typical High
$912.01
Aetna
Setting
Professional
Modifier
None (both parts)
Typical Low
$190.55
Median
$346.74
Typical High
$724.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$223.87
Typical High
$831.76
Cigna
Setting
Professional
Modifier
None (both parts)
Typical Low
$97.72
Median
$245.47
Typical High
$288.40
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$436.52
Typical High
$2,089.30
Highmark BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$54.95
Median
$54.95
Typical High
$54.95
United
Setting
Professional
Modifier
None (both parts)
Typical Low
$138.04
Median
$295.12
Typical High
$831.76

Where Delaware sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Delaware· 47th of 51

$269

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.