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In Situ Hybridization Tissue Test

Delaware rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$245

Typical negotiated rate. In Delaware, July 2026.

Insurers have agreed to pay about $245 for this service. Most negotiated rates run $129 to $347.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $245 · 10th to 90th $129 to $380
$100.0$200.0$500.0$1.0Kprofessional $245

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$53.70
Median
$53.70
Typical High
$63.10
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$245.47
Typical High
$346.74
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$39.81
Typical High
$56.23
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$204.17
Typical High
$295.12
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$223.87
Typical High
$288.40
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$26.92
Median
$36.31
Typical High
$87.10
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$64.57
Median
$173.78
Typical High
$223.87
Highmark BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$53.70
Median
$53.70
Typical High
$54.95
United
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$295.12
Typical High
$933.25
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$40.74
Median
$64.57
Typical High
$151.36
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$104.71
Median
$275.42
Typical High
$776.25

Where Delaware sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Delaware $245 · 47th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.