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In Situ Hybridization Tissue Test

Washington, DC rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$355

Typical negotiated rate. In Washington, DC, July 2026.

Insurers have agreed to pay about $355 for this service. Most negotiated rates run $309 to $355.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $355 · 10th to 90th $302 to $355
$5.0$20.0$100.0$500.0$2.0Kprofessional $355

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$354.81
Typical High
$354.81
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$51.29
Typical High
$51.29
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$257.04
Median
$309.03
Typical High
$309.03
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$56.23
Median
$354.81
Typical High
$398.11
CareFirst
Setting
Professional
Modifier
26 · Professional part
Typical Low
$52.48
Median
$53.70
Typical High
$70.79
CareFirst
Setting
Professional
Modifier
TC · Technical part
Typical Low
$147.91
Median
$302.00
Typical High
$407.38
Cigna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$234.42
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$28.18
Median
$35.48
Typical High
$218.78
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$190.55
Typical High
$1,288.25
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$933.25
Typical High
$933.25
Kaiser Permanente
Setting
Professional
Modifier
26 · Professional part
Typical Low
$75.86
Median
$134.90
Typical High
$134.90
Kaiser Permanente
Setting
Professional
Modifier
TC · Technical part
Typical Low
$436.52
Median
$812.83
Typical High
$812.83
United
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$331.13
Typical High
$912.01
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$43.65
Median
$131.83
Typical High
$316.23
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$208.93
Median
$288.40
Typical High
$1,659.59

Where Washington, DC sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Washington, DC $355 · 19th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.