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In Situ Hybridization Tissue Test

Connecticut rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$282

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $282 for this service. Most negotiated rates run $229 to $537.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $282 · 10th to 90th $129 to $794
$200$500$1Kprofessional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$281.84
Typical High
$616.60
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$56.23
Typical High
$144.54
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$93.33
Median
$239.88
Typical High
$489.78
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$245.47
Typical High
$870.96
Anthem BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$35.48
Median
$74.13
Typical High
$162.18
Anthem BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$120.23
Median
$165.96
Typical High
$758.58
Cigna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$269.15
Typical High
$812.83
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$33.11
Median
$63.10
Typical High
$123.03
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$91.20
Median
$218.78
Typical High
$691.83
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$691.83
Typical High
$891.25
ConnectiCare
Setting
Professional
Modifier
26 · Professional part
Typical Low
$63.10
Median
$63.10
Typical High
$117.49
ConnectiCare
Setting
Professional
Modifier
TC · Technical part
Typical Low
$346.74
Median
$346.74
Typical High
$645.65
Health New England
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
United
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$426.58
Typical High
$1,202.26
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$66.07
Typical High
$162.18
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$190.55
Median
$363.08
Typical High
$891.25

Where Connecticut sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 39th of 51

$282

MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.