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In Situ Hybridization Tissue Test

Arizona rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$257

Typical negotiated rate. In Arizona, July 2026.

Insurers have agreed to pay about $257 for this service. Most negotiated rates run $245 to $355.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $257 · 10th to 90th $204 to $617
$5.0$20.0$100.0$500.0$2.0Kprofessional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$204.17
Median
$275.42
Typical High
$478.63
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$39.81
Median
$56.23
Typical High
$223.87
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$147.91
Median
$218.78
Typical High
$323.59
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$72.44
Median
$72.44
Typical High
$87.10
BCBS
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$269.15
Typical High
$371.54
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$41.69
Median
$43.65
Typical High
$58.88
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$218.78
Median
$223.87
Typical High
$309.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$229.09
Typical High
$501.19
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$63.10
Typical High
$91.20
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$85.11
Median
$169.82
Typical High
$426.58
Medica
Setting
Facility
Modifier
26 · Professional part
Typical Low
$281.84
Median
$281.84
Typical High
$281.84
Medica
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$263.03
Typical High
$2,570.40
Medica
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$53.70
Typical High
$398.11
Medica
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$208.93
Typical High
$2,187.76
United
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$245.47
Typical High
$562.34
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$37.15
Median
$57.54
Typical High
$125.89
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$89.13
Median
$208.93
Typical High
$467.74

Where Arizona sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Arizona $257 · 46th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.