go back

In Situ Hybridization Tissue Test

Alabama rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$288

Typical negotiated rate. In Alabama, July 2026.

Insurers have agreed to pay about $288 for this service. Most negotiated rates run $251 to $380.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $288 · 10th to 90th $245 to $380
$100.0$200.0$500.0$1.0K$2.0Kprofessional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
26 · Professional part
Typical Low
$67.61
Median
$67.61
Typical High
$67.61
Aetna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$288.40
Typical High
$380.19
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$48.98
Typical High
$67.61
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$208.93
Median
$239.88
Typical High
$316.23
Ambetter
Setting
Professional
Modifier
26 · Professional part
Typical Low
$81.28
Median
$81.28
Typical High
$81.28
BCBS
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$407.38
Typical High
$478.63
BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$70.79
Median
$70.79
Typical High
$83.18
BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$338.84
Median
$338.84
Typical High
$398.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$173.78
Typical High
$275.42
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$29.51
Median
$33.88
Typical High
$114.82
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$66.07
Median
$131.83
Typical High
$239.88
United
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$245.47
Typical High
$457.09
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$38.90
Median
$56.23
Typical High
$85.11
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$112.20
Median
$190.55
Typical High
$346.74

Where Alabama sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Alabama $288 · 36th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.