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In Situ Hybridization Tissue Test

Alaska rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated July 2026.

How much does In Situ Hybridization Tissue Test cost?

$617

Typical negotiated rate. In Alaska, July 2026.

Insurers have agreed to pay about $617 for this service. Most negotiated rates run $170 to $724.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $617 · 10th to 90th $170 to $1,820
$200.0$500.0$1.0K$2.0Kprofessional $617

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$218.78
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$47.86
Median
$60.26
Typical High
$295.12
Aetna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$120.23
Median
$158.49
Typical High
$1,230.27
Cigna
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$251.19
Cigna
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$30.90
Typical High
$83.18
Cigna
Setting
Professional
Modifier
TC · Technical part
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
Premera BCBS
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$1,819.70
Typical High
$2,137.96
Premera BCBS
Setting
Professional
Modifier
26 · Professional part
Typical Low
$87.10
Median
$275.42
Typical High
$338.84
Premera BCBS
Setting
Professional
Modifier
TC · Technical part
Typical Low
$194.98
Median
$1,548.82
Typical High
$1,778.28
Providence
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$251.19
Providence
Setting
Professional
Modifier
26 · Professional part
Typical Low
$30.90
Median
$30.90
Typical High
$83.18
Providence
Setting
Professional
Modifier
TC · Technical part
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
United
Setting
Professional
Modifier
Global
Typical Low
$407.38
Median
$616.60
Typical High
$1,445.44
United
Setting
Professional
Modifier
26 · Professional part
Typical Low
$67.61
Median
$97.72
Typical High
$281.84
United
Setting
Professional
Modifier
TC · Technical part
Typical Low
$346.74
Median
$512.86
Typical High
$1,148.15

Where Alaska sits

The same service costs 4.7 times more in Minnesota than in Rhode Island. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Alaska $617 · 5th of 51
MN $794RI $170

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.