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In Situ Hybridization Tissue Test

Alaska rates for HCPCS 88377

This laboratory test applies a labeled genetic probe directly to a tissue sample taken during a biopsy or surgery, allowing a pathologist to detect a specific gene or genetic sequence within the cells using microscopy. The results help confirm a diagnosis, such as determining the type of a tumor or the source of abnormal cells, and can guide decisions about treatment.

Rates data updated October 2026.

How much does In Situ Hybridization Tissue Test cost?

$891

Typical negotiated rate. In Alaska, October 2026.

Insurers have agreed to pay about $891 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $1,445 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$245 to $1,445
FacilityA hospital or hospital-owned outpatient department$1,445$891 to $1,549

How much rates vary

Facilitymedian $1,445 · 10th to 90th $676 to $2,089Professionalmedian $525 · 10th to 90th $200 to $1,585
$200$500$1K$2Kfacility $1,445professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$1,548.82
Median
$1,548.82
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$218.78
Typical High
$724.44
Cigna
Setting
Facility
Modifier
None
Typical Low
$891.25
Median
$891.25
Typical High
$891.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$251.19
Moda Health
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$1,174.90
Typical High
$2,187.76
Moda Health
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$245.47
Typical High
$724.44
Premera BCBS
Setting
Professional
Modifier
None
Typical Low
$524.81
Median
$1,584.89
Typical High
$1,584.89
Providence
Setting
Facility
Modifier
None
Typical Low
$891.25
Median
$1,445.44
Typical High
$2,089.30
Providence
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$251.19
United
Setting
Professional
Modifier
None
Typical Low
$407.38
Median
$954.99
Typical High
$1,445.44

Where Alaska sits

The same service costs 9.1 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alaska· 1st of 51

$891

AK $891AL $97.72

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.