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Biotinidase Enzyme Blood Test

Wyoming rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$23.44

Typical negotiated rate. In Wyoming, October 2026.

Insurers have agreed to pay about $23.44 for this service. The price depends on where it is billed: about $23.44 from a physician practice, and about $20.89 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$23.44$20.89 to $53.70
FacilityA hospital or hospital-owned outpatient department$20.89$16.98 to $25.12

How much rates vary

Facilitymedian $21 · 10th to 90th $17 to $34Professionalmedian $23 · 10th to 90th $11 to $54
$10$20$50facility $21professional $23

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$16.98
Typical High
$16.98
Aetna
Setting
Professional
Modifier
None
Typical Low
$16.98
Median
$16.98
Typical High
$16.98
BCBS Wyoming
Setting
Facility
Modifier
None
Typical Low
$20.89
Median
$20.89
Typical High
$25.12
BCBS Wyoming
Setting
Professional
Modifier
None
Typical Low
$20.89
Median
$25.70
Typical High
$53.70
BCBS Wyoming
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$14.79
Median
$18.20
Typical High
$38.02
BCBS Wyoming
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$4.27
Median
$5.25
Typical High
$10.72
Cigna
Setting
Facility
Modifier
None
Typical Low
$33.88
Median
$33.88
Typical High
$33.88
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.23
Median
$11.48
Typical High
$23.99
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$10.00
Typical High
$23.44

Where Wyoming sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Wyoming· 9th of 51

$23.44

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.