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Biotinidase Enzyme Blood Test

Washington rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$15.85

Typical negotiated rate. In Washington, October 2026.

Insurers have agreed to pay about $15.85 for this service. The price depends on where it is billed: about $15.14 from a physician practice, and about $25.12 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$15.14$10.47 to $16.22
FacilityA hospital or hospital-owned outpatient department$25.12$17.78 to $33.88

How much rates vary

Facilitymedian $25 · 10th to 90th $15 to $47Professionalmedian $15 · 10th to 90th $7 to $20
$10$20$50facility $25professional $15

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$15.85
Median
$15.85
Typical High
$51.29
Aetna
Setting
Professional
Modifier
None
Typical Low
$15.85
Median
$15.85
Typical High
$19.95
Asuris Northwest Health
Setting
Facility
Modifier
None
Typical Low
$12.59
Median
$18.62
Typical High
$46.77
Asuris Northwest Health
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$15.14
Typical High
$16.98
Cigna
Setting
Facility
Modifier
None
Typical Low
$11.75
Median
$30.90
Typical High
$43.65
Cigna
Setting
Professional
Modifier
None
Typical Low
$10.47
Median
$15.85
Typical High
$23.99
Molina
Setting
Professional
Modifier
None
Typical Low
$10.72
Median
$14.79
Typical High
$14.79
Pacific Source
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$25.12
Typical High
$33.88
Premera BCBS
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$29.51
Typical High
$46.77
Premera BCBS
Setting
Professional
Modifier
None
Typical Low
$13.18
Median
$15.14
Typical High
$20.42
Regence BlueShield
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$26.30
Typical High
$46.77
Regence BlueShield
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$15.14
Typical High
$16.98
United
Setting
Facility
Modifier
None
Typical Low
$16.98
Median
$20.42
Typical High
$20.42
United
Setting
Professional
Modifier
None
Typical Low
$7.08
Median
$7.59
Typical High
$19.05
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$7.59
Median
$16.98
Typical High
$30.20
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$7.94
Median
$7.94
Typical High
$10.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$3.16
Median
$3.16
Typical High
$4.07

Where Washington sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Washington· 34th of 51

$15.85

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.