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Biotinidase Enzyme Blood Test

Virginia rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$15.85

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $15.85 for this service. The price depends on where it is billed: about $12.59 from a physician practice, and about $23.44 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.59$11.75 to $15.85
FacilityA hospital or hospital-owned outpatient department$23.44$16.98 to $42.66

How much rates vary

Facilitymedian $23 · 10th to 90th $16 to $89Professionalmedian $13 · 10th to 90th $8 to $38
$10$100$1K$10Kfacility $23professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$15.85
Median
$41.69
Typical High
$100.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$13.18
Typical High
$32.36
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$16.98
Typical High
$67.61
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$8.32
Median
$8.32
Typical High
$12.88
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$79.43
Typical High
$107.15
Cigna
Setting
Facility
Modifier
Global
Typical Low
$17.38
Median
$37.15
Typical High
$77.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$8.91
Median
$11.22
Typical High
$23.99
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$16.98
Median
$20.42
Typical High
$25.12
Medcost
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$28.18
Typical High
$33.11
Medcost
Setting
Facility
Modifier
Global
Typical Low
$14.45
Median
$15.14
Typical High
$15.85
Medcost
Setting
Professional
Modifier
Global
Typical Low
$3.89
Median
$14.45
Typical High
$35.48
Sentara
Setting
Facility
Modifier
Global
Typical Low
$15.14
Median
$24.55
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$15.14
Median
$24.55
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$7.08
Median
$16.98
Typical High
$28.84
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$10.00
Typical High
$17.78

Where Virginia sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 38th of 51

$15.85

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.