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Biotinidase Enzyme Blood Test

Tennessee rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$13.18

Typical negotiated rate. In Tennessee, July 2026.

Insurers have agreed to pay about $13.18 for this service. The price depends on where it is billed: about $12.59 from a physician practice, and about $25.70 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.59$12.59 to $13.49
FacilityA hospital or hospital-owned outpatient department$25.70$16.98 to $61.66

How much rates vary

Facilitymedian $26 · 10th to 90th $13 to $93Professionalmedian $13 · 10th to 90th $9 to $19
$5$10$20$50$100facility $26professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$25.70
Typical High
$77.62
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$12.59
Typical High
$19.50
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$15.49
Median
$15.49
Typical High
$15.49
BCBS
Setting
Professional
Modifier
Global
Typical Low
$7.94
Median
$7.94
Typical High
$18.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$35.48
Typical High
$69.18
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.76
Median
$12.88
Typical High
$25.70
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$93.33
Median
$93.33
Typical High
$93.33
United
Setting
Facility
Modifier
Global
Typical Low
$7.08
Median
$16.98
Typical High
$16.98
United
Setting
Professional
Modifier
Global
Typical Low
$4.37
Median
$7.08
Typical High
$22.39

Where Tennessee sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 50th of 51

$13.18

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.