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Biotinidase Enzyme Blood Test

Tennessee rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$12.88

Typical negotiated rate. In Tennessee, October 2026.

Insurers have agreed to pay about $12.88 for this service. Most negotiated rates run $7.94 to $20.89.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $35 · 10th to 90th $13 to $60Professionalmedian $10 · 10th to 90th $6 to $20
$5$10$20$50$100facility $35professional $10

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$12.59
Median
$13.49
Typical High
$25.70
Aetna
Setting
Professional
Modifier
None
Typical Low
$12.59
Median
$13.18
Typical High
$19.50
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$6.31
Median
$6.61
Typical High
$10.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$2.51
Median
$2.69
Typical High
$4.07
Ambetter
Setting
Professional
Modifier
None
Typical Low
$15.49
Median
$15.49
Typical High
$15.49
BCBS Tennessee
Setting
Professional
Modifier
None
Typical Low
$7.94
Median
$8.71
Typical High
$18.62
Cigna
Setting
Facility
Modifier
None
Typical Low
$12.59
Median
$34.67
Typical High
$66.07
Cigna
Setting
Professional
Modifier
None
Typical Low
$7.76
Median
$10.96
Typical High
$23.99
United
Setting
Professional
Modifier
None
Typical Low
$4.79
Median
$7.08
Typical High
$20.89

Where Tennessee sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 48th of 51

$12.88

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.