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Biotinidase Enzyme Blood Test

South Carolina rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

Facilitymedian $42 · 10th–90th $13$910%5%10%10th90th$42Professionalmedian $13 · 10th–90th $13$250%50%90th$13$1.0$2.0$5.0$10.0$20.0$50.0$100.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$13.18
Median
$41.69
Typical High
$79.43
Aetna
Setting
Professional
Modifier
Global
Typical Low
$13.18
Median
$13.18
Typical High
$14.79
BCBS
Setting
Facility
Modifier
Global
Typical Low
$10.72
Median
$58.88
Typical High
$104.71
BCBS
Setting
Professional
Modifier
Global
Typical Low
$17.38
Median
$25.70
Typical High
$37.15
Cigna
Setting
Facility
Modifier
Global
Typical Low
$31.62
Median
$54.95
Typical High
$138.04
Cigna
Setting
Professional
Modifier
Global
Typical Low
$8.51
Median
$10.96
Typical High
$21.88
Medcost
Setting
Facility
Modifier
Global
Typical Low
$12.30
Median
$17.78
Typical High
$35.48
United
Setting
Facility
Modifier
Global
Typical Low
$9.33
Median
$16.98
Typical High
$20.89
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$10.23
Typical High
$23.44