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Biotinidase Enzyme Blood Test

Oklahoma rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$23.44

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $23.44 for this service. The price depends on where it is billed: about $12.59 from a physician practice, and about $30.20 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$12.59$10.00 to $15.85
FacilityA hospital or hospital-owned outpatient department$30.20$16.98 to $42.66

How much rates vary

Facilitymedian $30 · 10th to 90th $13 to $49Professionalmedian $13 · 10th to 90th $7 to $19
$10$20$50$100facility $30professional $13

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$12.59
Median
$16.98
Typical High
$81.28
Aetna
Setting
Professional
Modifier
Global
Typical Low
$12.59
Median
$12.59
Typical High
$16.98
BCBS
Setting
Facility
Modifier
Global
Typical Low
$23.44
Median
$32.36
Typical High
$45.71
BCBS
Setting
Professional
Modifier
Global
Typical Low
$15.85
Median
$15.85
Typical High
$15.85
Cigna
Setting
Facility
Modifier
Global
Typical Low
$10.96
Median
$25.70
Typical High
$45.71
Cigna
Setting
Professional
Modifier
Global
Typical Low
$7.41
Median
$10.23
Typical High
$23.99
Medica
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$16.22
Typical High
$93.33
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$9.77
Typical High
$22.39
United
Setting
Facility
Modifier
Global
Typical Low
$8.32
Median
$16.98
Typical High
$22.39
United
Setting
Professional
Modifier
Global
Typical Low
$7.08
Median
$9.55
Typical High
$14.45

Where Oklahoma sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 6th of 51

$23.44

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.