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Biotinidase Enzyme Blood Test

New Jersey rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$19.95

Typical negotiated rate. In New Jersey, July 2026.

Insurers have agreed to pay about $19.95 for this service. The price depends on where it is billed: about $14.45 from a physician practice, and about $37.15 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$14.45$13.18 to $19.50
FacilityA hospital or hospital-owned outpatient department$37.15$25.12 to $85.11

How much rates vary

Facilitymedian $37 · 10th to 90th $17 to $182Professionalmedian $14 · 10th to 90th $11 to $48
$10$100$1K$10Kfacility $37professional $14

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$38.90
Typical High
$107.15
Aetna
Setting
Professional
Modifier
Global
Typical Low
$10.72
Median
$14.45
Typical High
$47.86
Cigna
Setting
Facility
Modifier
Global
Typical Low
$19.50
Median
$37.15
Typical High
$77.62
Cigna
Setting
Professional
Modifier
Global
Typical Low
$10.23
Median
$16.22
Typical High
$46.77
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$6.76
Median
$8.51
Typical High
$19.05
Horizon BCBS
Setting
Facility
Modifier
Global
Typical Low
$16.98
Median
$10,471.29
Typical High
$23,988.33
Horizon BCBS
Setting
Professional
Modifier
Global
Typical Low
$10.00
Median
$14.79
Typical High
$19.05
United
Setting
Facility
Modifier
Global
Typical Low
$7.94
Median
$16.98
Typical High
$35.48
United
Setting
Professional
Modifier
Global
Typical Low
$6.76
Median
$10.00
Typical High
$23.44

Where New Jersey sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New Jersey· 17th of 51

$19.95

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.