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Biotinidase Enzyme Blood Test

Nebraska rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$39.81

Typical negotiated rate. In Nebraska, July 2026.

Insurers have agreed to pay about $39.81 for this service. The price depends on where it is billed: about $19.50 from a physician practice, and about $50.12 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$19.50$11.22 to $105
FacilityA hospital or hospital-owned outpatient department$50.12$24.55 to $91.20

How much rates vary

Facilitymedian $50 · 10th to 90th $12 to $204Professionalmedian $19 · 10th to 90th $10 to $112
$10$20$50$100$200facility $50professional $19

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$12.02
Median
$67.61
Typical High
$204.17
Aetna
Setting
Professional
Modifier
Global
Typical Low
$11.22
Median
$104.71
Typical High
$112.20
BCBS
Setting
Facility
Modifier
Global
Typical Low
$44.67
Median
$58.88
Typical High
$125.89
BCBS
Setting
Professional
Modifier
Global
Typical Low
$18.20
Median
$26.30
Typical High
$27.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$56.23
Median
$56.23
Typical High
$56.23
Cigna
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$32.36
Typical High
$40.74
Medica
Setting
Facility
Modifier
Global
Typical Low
$10.00
Median
$31.62
Typical High
$93.33
Medica
Setting
Professional
Modifier
Global
Typical Low
$7.59
Median
$10.00
Typical High
$20.89
Midlands
Setting
Professional
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$34.67
Midlands
Setting
Facility
Modifier
Global
Typical Low
$20.89
Median
$20.89
Typical High
$20.89
Oscar Health
Setting
Facility
Modifier
Global
Typical Low
$363.08
Median
$363.08
Typical High
$426.58
United
Setting
Facility
Modifier
Global
Typical Low
$7.08
Median
$15.14
Typical High
$16.98
United
Setting
Professional
Modifier
Global
Typical Low
$9.55
Median
$10.00
Typical High
$33.88

Where Nebraska sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Nebraska· 1st of 51

$39.81

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.