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Biotinidase Enzyme Blood Test

North Dakota rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated July 2026.

How much does Biotinidase Enzyme Blood Test cost?

$25.70

Typical negotiated rate. In North Dakota, July 2026.

Insurers have agreed to pay about $25.70 for this service. The price depends on where it is billed: about $28.18 from a physician practice, and about $12.02 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$28.18$15.85 to $33.88
FacilityA hospital or hospital-owned outpatient department$12.02$11.75 to $15.85

How much rates vary

Facilitymedian $12 · 10th to 90th $12 to $30Professionalmedian $28 · 10th to 90th $12 to $39
$5$10$20$50$100facility $12professional $28

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$11.75
Typical High
$30.20
Aetna
Setting
Professional
Modifier
Global
Typical Low
$11.75
Median
$11.75
Typical High
$50.12
BCBS
Setting
Professional
Modifier
Global
Typical Low
$24.55
Median
$33.88
Typical High
$38.02
Cigna
Setting
Professional
Modifier
Global
Typical Low
$19.50
Median
$19.50
Typical High
$24.55
Medica
Setting
Facility
Modifier
Global
Typical Low
$11.75
Median
$19.95
Typical High
$93.33
Medica
Setting
Professional
Modifier
Global
Typical Low
$4.07
Median
$9.33
Typical High
$28.84
United
Setting
Facility
Modifier
Global
Typical Low
$52.48
Median
$52.48
Typical High
$52.48
United
Setting
Professional
Modifier
Global
Typical Low
$4.07
Median
$17.38
Typical High
$25.70

Where North Dakota sits

The same service costs 3.2 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Dakota· 3rd of 51

$25.70

NE $39.81DC $12.59

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.