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Biotinidase Enzyme Blood Test

North Dakota rates for HCPCS 82261

A blood test that measures the activity of biotinidase, an enzyme the body needs to recycle the vitamin biotin. It is used mainly in newborn screening to detect biotinidase deficiency, a rare inherited condition.

Rates data updated October 2026.

How much does Biotinidase Enzyme Blood Test cost?

$21.88

Typical negotiated rate. In North Dakota, October 2026.

Insurers have agreed to pay about $21.88 for this service. The price depends on where it is billed: about $23.99 from a physician practice, and about $11.75 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$23.99$10.00 to $28.84
FacilityA hospital or hospital-owned outpatient department$11.75$11.75 to $25.12

How much rates vary

Facilitymedian $12 · 10th to 90th $12 to $78Professionalmedian $24 · 10th to 90th $7 to $34
$5$10$20$50$100$200facility $12professional $24

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$11.75
Median
$11.75
Typical High
$77.62
Aetna
Setting
Professional
Modifier
None
Typical Low
$11.75
Median
$11.75
Typical High
$19.50
BCBS
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$83.18
Typical High
$83.18
BCBS
Setting
Professional
Modifier
None
Typical Low
$21.88
Median
$28.84
Typical High
$33.88
BCBS
Setting
Professional
Modifier
22 · Increased work
Typical Low
$26.30
Median
$34.67
Typical High
$40.74
BCBS
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$4.37
Median
$5.75
Typical High
$6.76
Cigna
Setting
Professional
Modifier
None
Typical Low
$19.50
Median
$19.50
Typical High
$30.20
Medica
Setting
Facility
Modifier
None
Typical Low
$11.75
Median
$12.02
Typical High
$35.48
Medica
Setting
Professional
Modifier
None
Typical Low
$4.07
Median
$9.33
Typical High
$23.44
United
Setting
Professional
Modifier
None
Typical Low
$4.07
Median
$10.00
Typical High
$23.44

Where North Dakota sits

The same service costs 18.6 times more in Kansas than in Kentucky. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

North Dakota· 10th of 51

$21.88

KS $53.70KY $2.88

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.